HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation - Journal of Biological Chemistry
Post-translational modifications within tau paired helical filament nucleating motifs perturb microtubule interactions and oligomer formation - Journal of Biological Chemistry
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TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6* - Journal of Biological Chemistry
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CHIP-mediated hyperubiquitylation of tau promotes its self-assembly into the insoluble tau filaments - Chemical Science (RSC Publishing) DOI:10.1039/D1SC00586C
HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation - Journal of Biological Chemistry
Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate | Nature Communications
Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system | Life Science Alliance
Protein interaction networks in neurodegenerative diseases: From physiological function to aggregation - Journal of Biological Chemistry
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The general theory of first-order spatio-temporal distortions of Gaussian pulses and beams
Click-Particle Display for Base-Modified Aptamer Discovery | ACS Chemical Biology
Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate | Nature Communications
miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects | Stem Cell Research & Therapy | Full Text
Targeting RNA structures with small molecules | Nature Reviews Drug Discovery
Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders | Journal of Medicinal Chemistry
In vivo reprogramming reactive glia into iPSCs to produce new neurons in the cortex following traumatic brain injury | Scientific Reports
Cell-type-specific epigenetic effects of early life stress on the brain | Translational Psychiatry